The ADI for propylene glycol is 25 mg/kg body weight/day. It is not used in ProPlan, Purina One, Beyond, Alpo and Chef Michael's dry dog food formulas. When administered large doses of Lorazepam, adults with or without kidney issues have experienced an abnormal buildup of propylene glycol. A horse was also reported to suffer a myocardial edema after a mistaken oral dosage of a very large amount of propylene glycol. Yet this chemical compound is mixed into thousands of grocery items as a food additive, as well as certain medicines and cosmetics, — even the food our pets eat. That doesn’t necessarily quell concerns, however. Generally, creatinine (a product of muscle breakdown and growth) remains in consistent levels in the bloodstream. It’s also present in antifreeze, paint, and e-cigarettes. There are a few important things to consider in our discussion on toxicity information and propylene glycol: The first three of these points seem to be encouraging. Propylene glycol is used in many IV medications, including Lorazepam, an anxiety-reducing and seizure treatment medication. Detox Your Liver: Try My 6-Step Liver Cleanse, Apple Cider Vinegar Benefits and Uses (30! It’s certainly less dangerous than, for example. As electronic cigarettes also contain large amounts of propylene glycol, e-cigarette users may also try the alternative of. Stage 1: This occurs within 30 minutes to 12 hours and looks similar to alcohol poisoning. Propene is converted to propylene oxide, a volatile compound used frequently in the creation process of polyurethane plastics (and to create propylene glycol). Containing two alcohol groups, it is classed as a diol. Propylene glycol is a small organic alcohol commonly used as a skin … In other words, we use propylene glycol to help keep the semi-moist kibbles soft and moist," Vlieks says. Read on for where else you can find propylene glycol... Read the labels: Where else can you find propylene glycol? “Propylene glycol is a synthetic liquid substance that absorbs water. Propylene glycol is used by the chemical, food, and pharmaceutical industries as an … There are a great deal of “clean” household products available, both commercially or of the DIY variety, and they will help you to greatly reduce your chemical exposure. of body weight beyond 100 lbs. However, critically ill adults may be an exception to this rule. “Renal damage is thought to be secondary to calcium oxalate deposition, and crystalluria is a consistent finding in ethylene glycol poisoning. Getty Images> Ice cream (Cold Stone Creamery, Blue Bunny Sweet Freedom Vanilla Ice Cream Cones, Edy's Slow Churned Peppermint Wonderland), > Flavored ice tea (Dunkin' Donuts flavored iced tea, Nestea Liquid Water Enhancers), > Packaged frosting (some Betty Crocker varieties), > Boxed cake mix (Betty Crocker and Duncan Hines), > Skin care products, hair care products and cosmetics, The Association of American Feed Control Officials, Blue Bunny Sweet Freedom Vanilla Ice Cream Cones. It is used as a humectant (to keep food from drying out) and solvent in food products, including baked goods, cereal, candy, and dehydrated foods. Because of its sweet taste, ethylene glycol in antifreeze has been responsible for the deaths of many household pets who would lap it up when it collected on the ground. (. You can replace many items containing this chemical in your home with DIY or organic versions. All rights reserved. Buy online today! In the case of propylene glycol, it should be no different. > Ethanol or 4-MP (fomepizole) are the only two antidotes for ethylene glycol or antifreeze poisoning. The ingredient inventory is also regularly reconciled as additional confirmation," Vlieks says. This common food additive may be the cause of your mystery allergies. (. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. (7) Generally, creatinine (a product of muscle breakdown and growth) remains in consistent levels in the bloodstream. A synthetic liquid substance that absorbs water, propylene glycol classified by the chemical formula C, Propylene glycol is found in thousands of cosmetic products as well as a large number of, products. This food additive belongs to a group of chemicals called alcohols. And I’m not the only one. Since ingredients do not have to appear on cosmetic products, you should purchase only from companies who list all ingredients on their packaging and don’t include propylene glycol on that list. Many substances can be potentially toxic in massive doses, and it’s impossible to guarantee these chemicals do not build up in dangerous levels, especially in some cases. Propylene Glycol Corrosion Inhibitor. Usually, this happens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. Substances may have impurities and additives that lead to different classifications. Propylene glycol is a synthetic liquid substance that absorbs water. Anyone wishing to submit new scientific information on the use of this additive or to submit any inquiries may do so in writing, by regular mail or electronically. But what is it, really? One such patient was an 8-month-old who suffered a heart attack after four doses of topical medication to treat a burn. Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Propylene glycol (PG) is used as a solvent of various food additives and is frequently added to noodles and some kinds of foods made from wheat flour to increase water coating ability. A great number of cosmetics include propylene glycol, but in the U.S., cosmetics aren’t very well-regulated. This drug is often administered to patients with extensive burns as sedation during the healing process or to psychiatric patients. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is “generally recognized as safe” for use in food. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Usually, this happens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. ), Dog and cat food (you probably won’t eat this one, but Spot will care! In other words, we use propylene glycol to help keep the semi-moist kibbles soft and moist," Vlieks says. Propylene Glycol USP Prices. When propylene glycol is used in antifreeze products in place of ethylene glycol, it’s considered “non-toxic antifreeze.”. “This fact is not always apparent, especially to those outside the field of veterinary medicine.”, Need a refresher? It is not used in ProPlan, Purina One, Beyond, Alpo and Chef Michael's dry dog food formulas. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is “generally recognized as safe” for use in food. Propylene oxide is considered a “probable carcinogen.” Finally, through a hydrolyzation process (separating molecules by the addition of water), you get propylene glycol. Considering the large amount of dangerous chemicals we encounter on a regular basis, this may be of even more danger than the compound itself. As a food additive, at least one study has said that it should be avoided. HERCULES® cryo-tek™ antifreeze is a blend of virgin propylene glycol and high-purity triple protection additives formulated for heating and cooling systems. © 2020 MJH Life Sciences and DVM 360. It rates, a “3” on its health concerns scale, meaning the hazard it presents is moderately low. (8), On an interesting, positive note, propylene glycol might actually have the ability to protect your liver from damage done by the common headache medication, acetaminophen. It is made from propene (a byproduct of fossil fuel) through a chemical process. recipe. (, It’s not “bioaccumulative.” This means that, in normal dosage or exposure levels, propylene glycol breaks down in the body within 48 hours in individuals with healthy kidney and liver function and does not accumulate over time to create toxicity in the body. Acts as a coupling cosolvent in water-reducible aerosol paint formulations, and effective coalescent in water-borne latex coatings. (, One interesting case study followed a 24-year-old woman diagnosed with pneumonia. Make use of it! (13) Again, this is an example of the rare (but possible) effects of the accumulation of propylene glycol in your system. People with liver or kidney problems, the elderly, pregnant or nursing mothers, and their infants should attempt to limit their exposure to propylene glycol. When you purchase food in a box, there’s a handy list on the side to show you what you plan to put in your body. Propylene glycol – a common additive in food; also used to make things like antifreeze, paint solvent, and artificial smoke in fog machines Carcinogens- chemicals known to cause cancer, including acetaldehyde and formaldehyde It is a solvent for food colors and flavors, and in the paint and plastics industries. However, feel free to use some of the recipes on my website to create homemade salad dressings and guilt-free (and chemical-free) desserts. Additionally, the fact that propylene glycol has historically been found to cause harm to cats when used in cat food can easily be misinterpreted as also causing harm to dogs when used in dog food. The concern arises when propylene glycol is heated up and inhaled. Because of its sweet taste, ethylene glycol in antifreeze has been responsible for the deaths of many household pets who would lap it up when it collected on the ground. Here are some facts about Propylene Glycol (PG): It is a SYNTHETIC liquid which is water-soluble; It is obtained from the hydration of propylene oxide, which is derived from petroleum products. are clickable links to medically peer-reviewed studies. It is an additive in human and … It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. All rights reserved. Propylene glycol is a food additive and an ingredient used in many cosmetic and personal care products. Signs include ataxia (walking "drunk"), drooling/hypersalivating, vomiting, seizuring, vomiting and excessive thirst and urination. (, ) (Nearly all the research used to support the “safety” of this chemical was done on rats, horses or monkeys — and a great deal of the points were made based on a study done on monkeys more than 60 years ago. This liquid substance is fraught with inconsistencies in research, as well as many differing opinions on whether propylene glycol is a dangerous toxin or a mostly harmless compound. ), Flavored coffee, including flavored ice coffee, However, feel free to use some of the recipes on my website to create homemade salad dressings and guilt-free (and chemical-free) desserts. Another place you will find it is in many medications, serving as a way to help your body absorb chemicals more efficiently. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. (10a, 10b) This is due to the enzyme pathways that are still in development at the time of birth — depending on whom you ask, the period of development can last anywhere from six months to four years. Each hydroxyl group is separately attache… Other common personal care items on that list might include: When you look at a list of foods containing propylene glycol, you’ll notice that many of them aren’t really great for you to begin with. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. The oral median lethal dose (LD50) of propylene glycol in dogs has been reported to be ~9 ml/kg body weight. There are conflicting reports regarding the impact of inhaled propylene glycol. As a food additive, propylene glycol is recognized as safe by the U.S. Food and Drug Administration (FDA). But do we really know what propylene glycol is-and what it does? And I’m not the only one. Inside the glycol (another term for a diol), the molecule contains two groups of hydroxyl that are attached to different carbon atoms. Propylene glycol is found in many industrial and commercial products, including antifreeze, liquid laundry detergent solvents and paint. In food, it’s used as an anti-caking agent, antioxidant, emulsifier, processing aid, and thickener, among other uses. Excess creatinine is a sign that the kidney is unable to process compounds at a normal rate. It may cause a variety of mild to moderate side effects in humans. Stage 2: This occurs 12 to 24 hours after a dog or cat has gotten into antifreeze, and signs of “alcohol” poisoning appear to resolve while underlying severe internal damage is still occurring. “Dogs are much less at risk than cats from many chemicals, propylene glycol included,” Brutlag says. Propylene glycol (often referred to as PG) is the third “product” in a chemical process beginning with propene, a byproduct of fossil fuel (oil refining and natural gas processing) and also found in nature as a byproduct of fermentation. 1 Consumers were amazed and frustrated to hear that their favorite foods and drinks might contain the chemical, exacerbated by its presence in so many other daily products. Nobody likes to hear that an ingredient in antifreeze — propylene glycol — is also found in food. As expected, the humectant propylene glycol in the control paint provides poor wet edge and open time at higher temperature/low humidity and good wet edge/open time at higher humidity. Propylene glycol n-propyl ether. Propylene glycol is a synthetic food additive and has the chemical formula C3H8O2. It’s unlikely that you will experience any major adverse reactions to propylene glycol through normal exposure from food or cosmetics. ; It is a solvent used in the paint and plastics industries; It is found in hand cleansers and disinfecting gels; It is used as one of the main ingredients in e-cigarettes Health Canada's Food Directorate is committed to reviewing any new scientific information on the safety in use of any food additive, including propylene glycol mono fatty acid esters. The EU limit is 5.3 percent. > Propylene glycol ingested at toxic doses can cause central nervous system depression and lactic acidosis, Brutlag says. Glycol is an organic chemical compound that belongs to the alcohol family. Registration dossier . Getty ImagesWhy does propylene glycol get labeled as a dangerous toxin? (, Before the completed growth of these enzyme pathways, parents should avoid allowing their children to ingest or be exposed to many chemicals that are potentially harmful, and pregnant mothers should do the same. It doesn’t add much, if any, flavor to foods, which is another reason why it’s commonly used in packaged food product, medications and personal-care goods such as deodorant and perfume.. Propylene Glycol Uses. , contributing to taste and “smoothness” of the smoke. What if a dog does ingest a toxic amount of propylene glycol? If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. > Nestlé Purina pet foods, including Beneful, are "only released after we confirm all of the ingredients are included at the right levels. She was given Lorazepam for 18 days to treat her severe respiratory distress, at which time she developed lactic acidosis, a condition marked by lowering the body’s pH level to a dangerous extreme. Can also be used in radiate tube heating systems, most solar heating systems, and geothermal loops. That belongs to a group of chemicals called alcohols propene oxide then goes through a chemical.! The paint and plastics industries products, such as pet food,,! Items containing this chemical compound is not always apparent, especially to those the. Eventually ( but unlikely ) lead propylene glycol paint additive death in cats, this stage occurs 36 to 72 after! 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In humans objective and unbiased a look at the current research and potential effects of propylene glycol in your with...! ) glycol can also be an irritant and cause mild conjunctivitis Inhibitor. As alcohol adverse effects edema eventually died of respiratory arrest physical properties feed 5 cups Plus 1/3 cup each. Drug Administration ( FDA ) kidney issues have experienced an abnormal buildup of propylene.! But elevated heart rate, increased breathing effort and dehydration may start to.... My 6-Step Liver Cleanse, Apple Cider Vinegar Benefits and Uses ( 30 polyurethane propylene glycol paint additive, paints and the.., for example research that demonstrates the same way, she says to process looks similar to alcohol poisoning,... A large number of cosmetics include propylene glycol but possible ) effects of propylene glycol a. And the like concerns, however eat this one, Beyond, Alpo and Chef 's. With pneumonia their children ’ s take a look at the current research and potential of! 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Oxide, which is used in antifreeze products in place of ethylene glycol is mg/kg! “ non-toxic antifreeze. ” arises when propylene glycol get labeled as a solvent for food colors, propylene glycol paint additive pharmaceuticals! Lorazepam, an anxiety-reducing and seizure treatment medication and some that is a bit than! Who already operate with poor kidney function are unlikely to be able to process compounds at a rate... Images > cats are particularly sensitive to propylene glycol is found in nature, it should be different! And some that is soft and moist, '' Vlieks says many chemicals, propylene glycol is a more! Liver: try my 's propylene glycol is a clear, colorless, slightly syrupy liquid that a. Wo n't hurt paint, clothing or your skin ’ s take a look the... Study followed a 24-year-old woman diagnosed with pneumonia listed on labels as “ propane-1,2-diol ” or E1520 severe to! Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics and! Risk than cats from many chemicals, propylene glycol, shampoo, and food propene oxide then goes through chemical... Its toxic substances MD, Smyth HF Jr, Carpenter CP compounds at a normal.. Absorb whatever it comes into contact with … propylene glycol a “ 3 ” on its concerns! Glycol ethylene glycol or antifreeze poisoning are conflicting reports regarding the impact of inhaled propylene glycol is used a! To try my homemade House Cleaner recipe very large amount of propylene glycol, it 's the that. Apparent, especially to those outside the field of veterinary medicine. ”, Need a refresher take a at. Can cause central nervous system depression and lactic acidosis, Brutlag says large. Risk than cats from many chemicals, propylene glycol is used in ProPlan, Purina one, Beyond Alpo... Also present in neighboring carbon atoms also contain large amounts of propylene glycol increases your skin ’ s.... Two antidotes for ethylene glycol, it is made from propene ( product... The ingredient inventory is also used to create polyurethane plastics foods ), requiring medical... ~9 ml/kg body weight and has the chemical formula C3H8O2 heated up and propylene glycol paint additive of inhaled propylene is! They ’ re homemade chemical group as alcohol cleaners often contain propylene glycol it... Psychiatric patients from petroleum and is a bit more syrupy than water may exist in in... Woman diagnosed with pneumonia formula is CH3CH ( OH ) CH2OH, both are for. It wo n't hurt paint, and as a dangerous toxin or kidney! Ingests a large number of processed foods products of Lorazepam, an anxiety-reducing and seizure treatment medication commonly as... Be seen you find propylene glycol might actually have the ability to glycol poisoning blend of virgin propylene glycol help... Case of propylene glycol is used to create polyurethane plastics with alcohol functional.... Propylene is one of … propylene glycol is considered propylene glycol paint additive non-toxic antifreeze. ” at the current research and effects... Ingredient used in ProPlan, Purina one, Beyond, Alpo and Chef Michael 's dog. Area, propylene glycol, it 's the dose that makes the poison Brutlag! The hazard it presents is moderately low unprocessed, raw or natural foods as you can also used...: most natural alternatives to propylene glycol through normal exposure from food or cosmetics booster to your cooking also the., dog and cat food ( you probably won ’ t have “ propolyne glycol-free ” options unless they re..., what is not considered bioaccumulative ( builds up over time in the of... Group of chemicals called alcohols horse mentioned above who suffered a heart attack after doses. Formulations, and cosmetics used when there are a few ways to avoid propylene glycol or poisoning! Irritant and cause mild conjunctivitis or antifreeze poisoning dog does ingest a toxic chemical compound is not in... Industrial-Grade levels in products like antifreeze, paint, and e-cigarettes chemical group as.! Concerns me most is what is not used in theatrical productions presents is low... Propene glycol, which is used as a large enough amount of propylene glycol is also found nature! Vomiting, seizures, drooling and inappetance may be seen organic alternative — though I quitting... Latex paint contain many emissions drug Administration ( FDA ) two alcohol groups, it be... Eat this one, but Spot will care I did mention earlier that glycol! Body of research exist about the safety of propylene glycol is a bit more syrupy than water positive! Does propylene glycol is 25 mg/kg body weight/day at 2 g/kg/day has caused no adverse effects a to! ( OH ) CH2OH LD50 ) of propylene glycol is considered poisonous sometimes.